Inês Pinto

PhD Student in Biotechnology


Research Activities

My research focuses on the development of innovative downstream processes for the purification of monoclonal antibodies based on multimodal chromatography, including both capture and polishing steps. The optimization of operating conditions using multimodal ligands is being performed in a collaboration between IBB and INESC Microsystems and Nanotechnologies, using microfluidic platforms for high-throughput screening purposes. I am also interested in exploring the use of chromatographic beads inside microchannels for biosensing applications.

 

 

Selected Publications

 

Pinto, I.F., Rosa, S.A.S.L, Aires-Barros, M.R., Azevedo, A.M., “Exploring the use of heparin as a first capture step in the purification of monoclonal antibodies from cell culture supernatants”, Biochem. Eng. J. (2015), 104, pp 27-33.

Pinto, I.F., Aires-Barros, M.R., Azevedo, A.M., “Multimodal chromatography: debottlenecking the downstream processing of monoclonal antibodies", Pharm Bioprocess (2015), 3(3), pp 263-279.

Pinto, I.F., Zhai, Y.C., Rosa, S.A.S.L, Aires-Barros, M.R., Azevedo, A.M., “Novel strategies for capturing monoclonal antibodies using alternative multimodal and electrostatic ligands”, Biopartitioning & Purification Conference 2015, Vienna, Austria | June 2015 (oral communication).

Pinto, I.F., Rosa, S.A.S.L, Aires-Barros, M.R., Azevedo, A.M., “A multimodal alternative for antibody capture from cell culture supernatants", ISPPP - 34th International Symposium on the Separation of Proteins, Peptides and Polynucleotides, Würzburg, Germany | November 2014 (poster communication).

 


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