Maria João Jacinto
PhD Student
Research Activities
Point of care, especially lateral flow assays and diagnostics are
becoming increasingly important. Many analytes often occur in low
concentrations, and usually in complex sample matrices such as
beverages and food, and body fluids, especially blood. For successful
application, these detection methods must be combined with effective
methods of sample processing, clean-up, and analyte concentration. The
methods used in sample processing for assays also often can find larger
applications, e.g., in manufacturing of viruses for vaccines and
therapeutics. I'm focused in the purification and detection of viruses,
virus like particles (VLPs) and bacteriophages as target analytes.
These tasks have been performed in iBB and Prof. Richard C. Willson's
lab, on the Department of Chemical and Biomolecular Engineering,
University of Houston.
Selected Publications
M.J. Jacinto, J. Trabuco, B.V. Vu, G. Garvey, A.M. Azevedo, M.R. Aires-Barros, K. Kourentzi, R.C. Willson, (2018) Enhancement of Lateral Flow Assay Performance by Electromagnetic Relocation of Reporter Particles to More-Visible Depths, PLos One, 13(1), doi: 10.1371/journal.pone.0186782
M.J. Jacinto, R.R.G. Soares, A.M. Azevedo, V. Chu, A. Tover, J.P. Conde, M.R. Aires-Barros, (2015) Optimization and miniaturization of aqueous two phase systems for the purification of recombinant human immunodeficiency virus-like particles from a CHO cell supernatant, Separation and Purification Technology, 154: 27-35, doi: 10.1016/j.seppur.2015.09.006
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