Nuno P. Mira

Assistant Professor

Research Activities

Current research interests are focused on: i) Physiology and molecular biology of Candida glabrata, Saccharomyces cerevisiae and Zygosaccharomyces bailii; ii) Regulation of gene and genomic expression in C. glabrata and S. cerevisiae under environmental stress; iii) Exploitation of S. cerevisae as a cell factory for the production of add-value chemicals; iv) Molecular mechanisms of pathogenesis in C. glabrata; v) Epidemiology of invasive fungal infections; vi) Development of molecular-based diagnosis tools for the early detection of invasive fungal infections

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Selected Publications

Nuno P. Mira, Sílvia Henriques, Greg Keller, Miguel C. Teixeira, Rute G. Matos, Cecília M. Arraiano, Dennis R. Winge and Isabel Sá-Correia, “Identification of a DNA binding site for the transcription factor Haa1p, required for Saccharomyces cerevisiae response to acetic acid stress”, Nucleic Acids Research, 16, 6896-907, (2011)

Mira NP, Teixeira MC and Sá-Correia I, “Adaptation and resistance to weak acids in Saccharomyces cerevisiae: a genome-wide view”, OMICS: a Journal of Integrative Biology, 14:5, 525-40, (2010)

Mira NP, Palma M, Guerreiro JF and Sá-Correia I, Genome-wide identification of Saccharomyces cerevisiae genes required for tolerance to acetic acid, Microbial Cell Factories, 9:79, (2010)

Guerreiro JF, Mira NP and Sá-Correia I, Adaptive response to acetic acid in the highly resistant species Zygosaccharomyces bailii revealed by quantitative proteomics, Proteomics, 12(14): 2303-18, (2012)

Teixeira MC, Mira NP and Isabel Sá-Correia, “A genome-wide perspective on food-relevant stress responses in yeast”, Current Opinion in Biotechnology, 22:150-6, (2011)

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