Raquel Aires-Barros
Full Professor

Research Activities
Current research interests include bioseparation of antibodies and cells through aqueous two-phase systems and chromatography, and application of lab-on-a-chip microfluidic devices to biopharmaceuticals separation and process integration.

Selected Publications
Campos-Pinto I, Espitia-Saloma E, Rosa SASL, Rito-Palomares M, Aguilar O, Arévalo-Rodríguez M, Aires-Barros MR, Azevedo AM  (2017) Integration of cell harvest with affinity-enhanced purification of monoclonal antibodies using aqueous two-phase systems with a dual tag ligand, Separation and Purification Technology 173: 129–134, doi.org/10.1016/j.seppur.2016.09.017

Silva DFC, Azevedo AM, Fernandes P, Chu V, Conde JP, Aires-Barros MR  (2017) Determination of partition coefficients of biomolecules in a microfluidic aqueous two phase system platform using fluorescence microscopy, Journal of Chromatography A, 1487: 242–247, doi.org/10.1016/j.chroma.2016.12.036

Bras EJS, Soares RRG, Azevedo AM, Fernandes P, Arévalo- Rodríguez M, Chu V, Conde JP, Aires-Barros MR (2017) A multiplexed microfluidic toolbox for the rapid optimization of affinity-driven partition in aqueous two phase systems, Journal of Chromatography A, 1515: 252–259, doi.org/10.1016/j.chroma.2017.07.094

Jacinto MC, Patinha DJS, Marrucho IM, Goncalves J, Willson RC, Azevedo AM, Aires-Barros MR (2018) M13 bacteriophage purification using poly(ionic liquids) as alternative separation matrices, Journal of Chromatography A, 1532: 246–250, doi.org/10.1016/j.chroma.2017.12.005

Campos-Pinto I, Capela E, Silva-Santos AR, Rodriguez MA, Gavara PR, F-Lahore M, Aires-Barros MR, Azevedo AM (2018) LyTag-driven purification strategies for monoclonal antibodies using quaternary amine ligands as affinity matrices, J Chem Technol Biotechnol, 93: 1966–1974, doi 10.1002/jctb.5460

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