Rogério Gaspar
Full Professor
Head of Department of Pharmacy Practice at the School of Pharmacy, University of Lisbon

Research Activities
Research interests include the development of new therapeutic strategies using drug delivery systems (nanomedicines) including liposomes, polymeric biodegradable nanoparticles, and polymer therapeutics, with the main focus oriented towards cytosolic delivery of nucleic acids and use of targeted delivery systems for combination therapy or therapeutic vaccines in cancer and infectious diseases.
Further to his scientific background in nanomedicine (since 1986), has also a long standing global expertise in regulatory affairs and regulatory science, including quality managing systems (since 1995).
Previously at University of Coimbra/CNC until 2006, and at iMed.ULisboa from 2007 until April 30th (2017).

Selected Publications
Luísa Corvo, T.M., Mendo, A.S., Figueiredo, S., Gaspar, R., Larguinho, M., Guedes da Silva M.F.C., Baptista, P.V., Fernandes, A.R., Liposomes as Delivery System of a Sn (IV) Complex for Cancer Therapy, Pharmaceutical Research 33 (6), 1351-1358 (2016)

Silva, J.M., Videira, M., Gaspar, R., Préat, V., Florindo, H.F., Immune system targeting by biodegradable nanoparticles for cancer vaccines, Journal of Controlled Release 168 (2), 179-199 (2013)

Duncan, R., Gaspar, R. , Nanomedicine (s) under the microscope, , Molecular Pharmaceutics 8 (6), 2101-2141 (2011)

Klopp, A.H., Lacerda, L., Gupta, A., Debeb, B.G., Solley, T., Li, L., Spaeth, E., Xu, W., Zhang, X., Lewis, M.T., Reuben, J.M., Krishnamurthy, S., Ferrari, M., Gaspar, R., Buchholz, T.A, Cristofanilli, M., Marini, F., Andreeff, M., Woodward, W.A., Mesenchymal stem cells promote mammosphere formation and decrease E-cadherin in normal and malignant breast cells, PloS one 5 (8), e12180 (2010)

Gaspar, R., Duncan, R., Polymeric carriers: preclinical safety and the regulatory implications for design and development of polymer therapeutics, Advanced Drug Delivery Reviews 61 (13), 1220-1231 (2009)

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