Tiago Fernandes

Assistant professor

Research Activities

My research is focused on providing an integrated platform that brings together engineering and biology in order to accelerate progress towards designing the stem cell fate and its microenvironment. My goal is to contribute to the development of innovative cell culture models that better reflect in vivo function, and the final objective is to generate cells and tissues to advance our understanding of biology and tissue regeneration, which will lead to further development of cell-based therapies.

Selected Publications

Barbosa H.S.C., Fernandes T.G., Dias T.P., Diogo M.M., Cabral J.M.S., "New Insights into the Mechanisms of Embryonic Stem Cell Self-Renewal under Hypoxia: a Multifactorial approach", PLoS ONE, 7(6): e38963 (2012)

Fernandes, T.G., Diogo, M.M., Fernandes-Platzgummer, A.M., Lobato da Silva, C., Cabral, J.M.S., "Different Stages of Pluripotency Determine Distinct Patterns of Proliferation, Metabolism and Lineage Commitment of Embryonic Stem Cells under Hypoxia", Stem Cell Research, 5: 76-89 (2010)

Fernandes, T.G., Kwon, S.J., Bale, S.S., Lee, M.Y., Diogo, M.M., Clark, D.S., Cabral, J.M.S., Dordick, J.S., "Three-Dimensional Cell Culture Microarray for High-Throughput Studies of Stem Cell Fate", Biotechnology and Bioengineering, 106: 106-118 (2010)

Fernandes, T.G., Diogo, M.M., Clark, D.S., Dordick, J.S., Cabral, J.M.S., "High-Throughput Cellular Microarray Platforms: Potential Applications in Drug Discovery, Toxicology and Stem Cell Research", Trends in Biotechnology, 27: 342–349 (2009)

Fernandes, T.G., Kwon, S.J., Lee, M.Y., Clark, D.S., Cabral, J.M.S., Dordick, J.S., "On-Chip, Cell-Based Microarray Immunofluorescence Assay for High-Throughput Analysis of Target Proteins", Analytical Chemistry, 80: 6633–6639 (2008)

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