Ana Ester Ventura
PhD student

Research Activities

I’m interested in unravelling the mechanism by which ceramides exerts its biological effects. Ceramides are a family of sphingolipids with distinct biophysical properties, different ceramides may have different biophysical properties and the hypothesis that I’m working on is that the biological effect it’s related with these biophysical alterations.

Selected Publications

Lopes RMRM, Ventura AE, Silva LC, Faustino H, Gois PMP. (2018) N,O-Iminoboronates: Reversible Iminoboronates with Improved Stability for Cancer Cells Targeted Delivery., Chemistry. 24(48):12495-12499. doi: 10.1002/chem.201802515

Varela AR, Ventura AE, Carreira AC, Fedorov A, Futerman AH, Prieto M, Silva LC. (2016) Pathological levels of glucosylceramide change the biophysical properties of artificial and cell membranes. Phys Chem Chem Phys. 19(1):340-346. doi: 10.1039/c6cp07227e.

Carreira AC, Ventura AE, Varela AR, Silva LC.  Tackling the biophysical properties of sphingolipids to decipher their biological roles. Biol Chem. 396(6-7):597-609. doi: 10.1515/hsz-2014-0283


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