Ana Rita Santos
PhD student



Research Activities

My main research interests are on the fields of Biotechnology and Bioprocess Engineering, especially on downstream processing. My current research focus on (i) the development of scalable processes for the biomanufacturing of scaffolds and DNA-origami nanostructures, and (ii) the study of the possibility of using fluorescently labelled DNA nanostructures in bio-imaging applications.

Selected Publications

Campos‐Pinto, I., Capela, E. V., Silva‐Santos, A. R., Rodríguez, M. A., Gavara, P. R., Fernandez‐Lahore, M., ... & Azevedo, A. M. (2017). LYTAG‐driven purification strategies for monoclonal antibodies using quaternary amine ligands as affinity matrices. Journal of Chemical Technology & Biotechnology. 93(7): 1966-1974, doi: 10.1002/jctb.5460

Silva-Santos, A. R., Alves, C. P., Prazeres, D. M. F., & Azevedo, A. M. (2017). A process for supercoiled plasmid DNA purification based on multimodal chromatography. Separation and Purification Technology. 182: 94-100, doi: 10.1016/j.seppur.2017.03.042

Silva-Santos, A. R., Alves, C. P., Prazeres, D. M. F., & Azevedo, A. M. (2016). Separation of plasmid DNA topoisomers by multimodal chromatography. Analytical biochemistry. 503: 68-70, doi: 10.1016/j.ab.2016.03.012

Silva-Santos AR, Alves CPA, Šimčiková M, Monteiro GA, Azevedo AM, Prazeres DMF, Multimodal chromatography of supercoiled minicircles: a closer look into DNA-ligand interactions. 2017. Oral Presentation at MicroBiotec’18 in Porto, Portugal.

Silva-Santos AR, Alves CPA, Šimčiková M, Monteiro GA, Azevedo AM, Prazeres DMF, Combining enzymatic topology modification and multimodal chromatography for minicircle purification. Oral Presentation at II International Congress in Health Sciences Research in Covilhã, Portugal

 

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