Maria João Jacinto
PhD Student

Research Activities

Point of care, especially lateral flow assays and diagnostics are becoming increasingly important. Many analytes often occur in low concentrations, and usually in complex sample matrices such as beverages and food, and body fluids, especially blood. For successful application, these detection methods must be combined with effective methods of sample processing, clean-up, and analyte concentration. The methods used in sample processing for assays also often can find larger applications, e.g., in manufacturing of viruses for vaccines and therapeutics. I'm focused in the purification and detection of viruses, virus like particles (VLPs) and bacteriophages as target analytes. These tasks have been performed in iBB and Prof. Richard C. Willson's lab, on the Department of Chemical and Biomolecular Engineering, University of Houston.

Selected Publications

M.J. Jacinto, D. J. S. Patinha, I. M. Marrucho, J. Gonçalves, R. C. Willson, A. M. Azevedo, R. Aires Barros, (2018) M13 Bacteriophage Purification Using Poly(Ionic Liquids) as Alternative Separation Matrices, Journal of Chromatography A, 1532: 246-250, doi: 10.1016/j.chroma.2017.12.005

M.J. Jacinto, J. Trabuco, B.V. Vu, G. Garvey, A.M. Azevedo, M.R. Aires-Barros, K. Kourentzi, R.C. Willson, (2018) Enhancement of Lateral Flow Assay Performance by Electromagnetic Relocation of Reporter Particles to More-Visible Depths, PLos One, 13(1), doi: 10.1371/journal.pone.0186782

M.J. Jacinto, R.R.G. Soares, A.M. Azevedo, V. Chu, A. Tover, J.P. Conde, M.R. Aires-Barros, (2015) Optimization and miniaturization of aqueous two phase systems for the purification of recombinant human immunodeficiency virus-like particles from a CHO cell supernatant, Separation and Purification Technology, 154: 27-35, doi: 10.1016/j.seppur.2015.09.006


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