Carla P. Coutinho
Post-Doctoral Researcher

Research Activities
- Epidemiology and elucidation of adaptive evolution mechanisms adopted by Burkholderia cepacia complex bacteria in respiratory infections of cystic fibrosis patients during long-term lung infection,
- New persistence and virulence factors and mechanisms that may inspire new therapeutic strategies to treat severe chronic respiratory infections,
- The Burkholderia cepacia complex bacteria as contaminants of medicines and medical devices,
- Molecular and Cellular Microbiology,
- Functional and Comparative Genomics and Biospectroscopy,

Selected Publications
Hassan AA, Maldonado RF, Sandra Costa dos Santos SC, Di Lorenzo F, Silipo A, Coutinho C, Cooper V S, Molinaro A, Valvano MA, Sá-Correia I (2017) Structure of O-antigen and hybrid biosynthetic locus in Burkholderia cenocepacia clonal variants recovered from a cystic fibrosis patient, Frontiers in Microbiology, doi: 10.3389/fmicb.2017.01027

Moreira AS, Mil-Homens D.*, Sousa SA*, Coutinho CP*, Pinto-de-Oliveira A, Ramos CG, dos Santos SC, Fialho AM, Leitão JH, Sá-Correia I (2016) Variation of Burkholderia cenocepacia virulence potential during cystic fibrosis chronic lung infection. Virulence, 21:1-15 doi: 10.1080/21505594.2016.1237334

Coutinho CP, Barreto C, Pereira L, Lito L, Melo Cristino J, Sá-Correia I (2015) Incidence of Burkholderia contaminans at a cystic fibrosis centre with an unusually high representation of Burkholderia cepacia during 15 years of epidemiological surveillance, Journal of Medical Microbiology. 64(8):927-35, doi: 10.1099/jmm.0.000094

Madeira A, Dos Santos SC, Santos PM, Coutinho CP, Tyrrell J, McClean S, Callaghan M, Sá-Correia I (2013) Proteomic profiling of Burkholderia cenocepacia clonal isolates with different virulence potential retrieved from a cystic fibrosis patient during chronic lung infection. PLoS One. 8:e83065,v 2014, doi: 10.1371/journal.pone.0083065

Coutinho CP, dos Santos SC, Madeira A, Mira NP, Moreira AS, Sá-Correia I (2011) Long-term colonization of the cystic fibrosis lung by Burkholderia cepacia complex bacteria: epidemiology, clonal variation, and genome-wide expression alterations. Frontiers in Cellular and Infection Microbiology. 1: 1-11, 2011, doi: 10.3389/fcimb.2011.00012

E-mail (click on)

Alternative webpages
Google Scholar
Research ID