Cláudia P. Godinho
Post-doc researcher

Research Activities
• Understanding and manipulating tolerance to multiple stresses in the cell factory Saccharomyces cerevisae;
• Multidrug/multixenobiotic resistance (MDR/MXR) membrane transporters;
• Yeast toxicogenomics;
• Functional analysis of homologous transporters in the plant model Arabidopsis thaliana and design of plants resistant to agricultural stresses (in collaboration).

Selected Publications
Godinho CP, Prata CS, Pinto SN, Cardoso C, Bandarra NM, Fernandes F, Sá-Correia I (2018) Pdr18 is involved in yeast response to acetic acid stress counteracting the decrease of plasma membrane ergosterol content and order, Sci. Rep.-UK 8(1):7860. doi: 10.1038/s41598-018-26128-7.

Teixeira MC, Monteiro PT, Palma M, Costa C, Godinho CP, Pais P, Cavalheiro M, Antunes M, Lemos A, Pedreira T. and Sá-Correia I (2018) YEASTRACT: an upgraded database for the analysis of transcription regulatory networks in Saccharomyces cerevisiae, Nucleic Acids Res. 46(D1):D348-D353. doi: 10.1093/nar/gkx842.

Remy E, Niño-González M, Godinho CP, Cabrito TR, Teixeira MC, Sá-Correia I, Duque P (2017) Heterologous expression of the yeast Tpo1p or Pdr5p membrane transporters in Arabidopsis confers plant xenobiotic tolerance, Sci. Rep.-UK 7(1):4529. doi: 10.1038/s41598-017-04534-7.

Godinho CP, Mira NP, Cabrito TR, Teixeira MC, Alasoo K, Guerreiro JF, Sá-Correia I (2017) Yeast response and tolerance to benzoic acid involves the Gcn4- and Stp1- regulated multidrug/multixenobiotic resistance transporter Tpo1, Appl. Microb. Biot. 101: 5005. doi:10.1007/s00253-017-8277-6.

Teixeira MC, Godinho CP, Cabrito TR, Mira NP, Sá-Correia I (2012) Increased expression of the yeast multidrug resistance ABC transporter Pdr18 leads to increased ethanol tolerance and ethanol production in high gravity alcoholic fermentation, Microb. Cell Fact. 11:98. doi: 10.1186/1475-2859-11-98.

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