Carlos Rodrigues

Research Activities
My research at iBB/SCERG focuses on the development and operation of bioreactor culture systems for the large-scale expansion and controlled differentiation of human Plutipotent Stem Cells (hPSC) and hPSC-derived cells, maintaining biological functionality and safety in a reproducible manner, for regenerative medicine therapies and for drug discovery.

Selected Publications
Rodrigues CAV, Silva TP, Nogueira DES, Fernandes TG, Hashimura Y, Wesselschmidt R, Diogo MM, Lee B, Cabral JMS (2018) Scalable Culture Of Human Induced Pluripotent Cells On Microcarriers Under Xeno‐Free Conditions Using Single‐Use Vertical‐Wheel™ Bioreactors,  J Chem Technol Biotechn ol, doi:10.1002/jctb.5738 [Epub ahead of print]

Badenes SM, Fernandes TG, Miranda CC, Pusch-Klein A, Haupt S, Rodrigues CAV, Diogo MM, Brüstle O, Cabral JMS (2017) Long-term expansion of human induced pluripotent stem cells in a microcarrier-based dynamic system, J Chem Technol Biotechnol 92: 492–503, doi:10.1002/jctb.5074
Badenes SM, Fernandes TG, Rodrigues CAV, Diogo MM, Cabral JMS (2016) Microcarrier-based platforms for in vitro expansion and differentiation of human pluripotent stem cells in bioreactor culture systems, J Biotechnol 234: 71-82, doi: 10.1016/j.jbiotec.2016.07.023

Pires F, Ferreira Q, Rodrigues CAV, Morgado J, Ferreira FC (2015) Neural stem cells differentiation by electrical stimulation using a cross-linked PEDOT substrate: expanding the use of biocompatible conjugated conductive polymers for neural tissue engineering, BBA-Gen Subjects 1850: 1158-1168, doi: 10.1016/j.bbagen.2015.01.020

Palma SICJ, Rodrigues CAV, Carvalho A, Morales Mdel P, Freitas F, Fernandes AR, Cabral JM, Roque AC (2015) A value-added exopolysaccharide as a coating agent for MRI nanoprobes, Nanoscale, 7: 14272 – 14283, doi:10.1039/c5nr01979f

E-mail (click on)

Alternative webpages