Joana R. Feliciano
Post-Doctoral Researcher

Research Activities
My research is focused on the understanding of the biological roles played by RNA binding proteins from bacteria of the Burkholderia cepacia complex (Bcc), with especial emphasis on their role in the regulation of bacterial virulence. I am also interested in using OMICs approaches to identify regulatory RNAs and their targets envisaging the deciphering of their biological roles.

Selected Publications
Mesureur J, Feliciano JR, Wagner N, Gomes MC, Zhang L, Blanco-Gonzalez M, van der Vaart M, O’Callaghan D, Meijer AH, Vergunst AC (2018) “Macrophages, but not neutrophils, are critical for proliferation of Burkholderia cenocepacia and ensuing host-damaging inflammation”. PLoS Pathogens. 13(6): e1006437. doi:10.1371/journal.ppat.1006437.

Sousa SA, Feliciano JR, Pita T, Guerreiro SI, Leitão JH. (2017). “Burkholderia cepacia complex virulence gene expression regulation: a review.” Genes. 8(1): 43. doi:10.3390/genes8010043.

Alves LG, Pinheiro PF, Feliciano JR, et al. (2017). “Synthesis and in vitro antimicrobial activity of cyclam derivatives.” Int J Antimicrob Agents. 49(5):646-­‐649. doi:10.1016/j.ijantimicag.2017.03.002.

Feliciano JR, Grilo AM, Guerreiro SI, Sousa SA, and Leitão JH (2016) "Hfq: a multifaceted RNA chaperone involved in virulence." Future Microbiol. 11:137-­‐151. doi: 10.2217/fmb.15.128.

Sousa SA*, Feliciano JR*, Pinheiro PF, and Leitão JH (2013) “Biochemical and functional studies on the Burkholderia cepacia complex bceN gene,    encoding    a    GDP-­‐D-­‐    mannose    4,6-­‐dehydratase”.    PLoS    ONE.    8:    e56902. doi: 10.1371/journal.pone.0056902. * Contributed equally to this work.

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