Numo Martinho

Research Activities
Nuno Martinho works on the development and synthesis of novel dendrimer-based macromolecules as functional polymeric materials for drug delivery by integrating in silico methods in the rational design and characterization of their properties and biological interactions.

Selected Publications
Martinho N, Santos TCB, Florindo HF, Silva LC (2018) Cisplatin-Membrane Interactions and Their Influence on Platinum Complexes Activity and Toxicity, Front. Physiol. 9: 1898, doi: 10.3389/fphys.2018.01898

Martinho N, Silva LC, Florindo HF, Brocchini S, Zloh M, Barata TS (2017) Rational design of novel, fluorescent, tagged glutamic acid dendrimers with different terminal groups and in silico analysis of their properties, Int. J. Nanomedicine 12:7053-7073 doi: 10.2147/IJN.S135475

Martinho N, Silva LC, Florindo HF, Brocchini S, Barata TS, Zloh M (2017) Practical computational toolkits for dendrimers and dendron structure design, J. Comput. Aided Mol. Des. 31(9): 817-827 doi: 10.1007/s10822-017-0041-6

Shah SU, Martinho N, Socha M, Pinto Reis C, Gibaud S (2015) Synthesis and characterization of S-nitrosoglutathione-oligosaccharide-chitosan as a nitric oxide donor, Expert. Opin. Drug Deliv. 12(8):1209-23

Martinho N, Florindo HF, Silva LC, Brocchini S, Zloh M, Barata T (2014) Molecular Modeling to Study Dendrimers for Biomedical Applications, Molecules 19(12): 20424-20467 doi: 10.3390/molecules191220424

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